郑积敏

个人简介

教授，博士生导师，理学博士（加拿大 女王大学），博士后（加拿大 女王大学）

通信地址：北京市新街口外大街19号 北京师范大学化学学院 501室
邮编：100875
电话：010 5880 6002； 传真：010 5880 6002
电子邮箱: jimin_z@bnu.edu.cn

讲授课程

1.化学与生活

2.天然资源产物

3.食品生物技术

研究兴趣

蛋白质结构和功能

代表性论文

1. J. Zheng, S. Yates and Z. Jia. (2012) Structural and mechanistic insights into the bifunctional enzyme isocitrate dehydrogenase kinase/phosphatase AceK. Philos. Trans. R. Soc. Lond. B Biol. Sci. in press.

2. J. Zheng and Z. Jia. (2010) Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase. Nature, 465, 961-965.

3. D. Lee, J. Zheng, Y.-M. She and Z. Jia. (2008) Structure of Escherichia coli tyrosine kinase Etk reveals novel activation mechanism. EMBO J. 27, 1758-1766

4. L. Qin, J. Zheng, C.E. Grant, Z. Jia, S. P. C. Cole and R.G. Deeley. (2008) Residues responsible for the asymmetric function of the nucleotide binding domains of Multidrug Resistance Protein (MRP) 1. Biochemistry, 47, 13952-13965.

5. J. Zheng, C. He, V. K. Singh, N.L. Martin and Z. Jia. (2007) Crystal structure of a novel prokaryotic Ser/Thr kinase and its implication in the Cpx stress response pathway. Mol. Mircobiol. 63, 1360-1371.

6. J. Zheng, V.K. Singh and Z. Jia. (2005) Identification of an ITPase/XTPase in E. coli by structural and biochemical analysis. Structure, 13, 1511-1520.